| First Authors |
Paulina J. Strzyz
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| Authors |
Paulina J. Strzyz, Marija Matejcic, Caren Norden
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| Corresponding Authors |
Paulina J. Strzyz, Caren Norden
|
| Last Authors |
Caren Norden
|
| Book Volume Title |
Volume 325 |
| Series Title |
International Review of Cell and Molecular Biology |
| Chapter Number |
3 |
| Publisher |
Elsevier |
| Book Editors |
Kwang W. Jeon
|
| ISBN |
978-0-12-804806-1 |
| First Page |
89 |
| Last Page |
114 |
| Open Access |
false |
| Print Publication Date |
2016-01-01 |
| Online Publication Date |
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| Abstract |
Pseudostratified epithelia (PSE) are tightly packed proliferative tissues that are important
precursors of the development of diverse organs in a plethora of species, invertebrate
and vertebrate. PSE consist of elongated epithelial cells that are attached to
the apical and basal side of the tissue. The nuclei of these cells undergo interkinetic
nuclear migration (IKNM) which leads to all mitotic events taking place at the apical
surface of the epithelium. In this review, we discuss the intricacies of proliferation in
PSE, considering cell biological, as well as the physical aspects. First, we summarize the
principles governing the invariability of apical nuclear migration and apical cell division
as well as the importance of apical mitoses for tissue proliferation. Then, we focus
on the mechanical and structural features of these tissues. Here, we discuss how the
overall architecture of pseudostratified tissues changes with increased cell packing.
Lastly, we consider possible mechanical cues resulting from these changes and their
potential influence on cell proliferation. |
| PDF |
Strzyz_2016_6546.pdf
(2.3 MB)
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| Cover Image |
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| Affiliated With |
Norden
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| Selected By |
Norden
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| Acknowledged Services |
Media Technology and Outreach
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| Publication Status |
Published |
| Edoc Link |
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| Sfx Link |
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| DOI |
10.1016/bs.ircmb.2016.02.004 |
| PubMed ID |
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| WebOfScience Link |
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| Alternative Full Text URL |
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| Display Publisher Download Only |
false |
| Visible On MPI-CBG Website |
true |
| PDF Downloadable |
true |
| Created By |
norden |
| Added Date |
2016-05-31 |
| Last Edited By |
thuem |
| Last Edited Date |
2017-12-11 16:39:55.447 |
| Library ID |
6546 |
| Document ID |
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| Entry Complete |
true |
| eDoc Compliant |
true |
| Include in Edoc Report |
true |
| In Pure |
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| Ready for eDoc Export |
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| Author Affiliations Complete |
false |
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