| First Authors | Nikitas Georgakopoulos |
|---|---|
| Authors | Nikitas Georgakopoulos, Nicole Prior, Brigitte Angres, Gianmarco Mastrogiovanni, Alex Cagan, Daisy Harrison, Christopher J Hindley, Robert Arnes-Benito, Siong-Seng Liau, Abbie Curd, Natasha Ivory, Benjamin D Simons, Inigo Martincorena, Helmut Wurst, Kourosh Saeb-Parsy, Meritxell Huch |
| Corresponding Authors | |
| Last Authors | Meritxell Huch |
| Journal Name | BMC developmental biology (BMC Dev Biol) |
| Volume | 20 |
| Issue | 1 |
| Article Number | 4 |
| Open Access | true |
| Print Publication Date | 2020-02-26 |
| Online Publication Date | |
| Abstract | Pancreatic organoid systems have recently been described for the in vitro culture of pancreatic ductal cells from mouse and human. Mouse pancreatic organoids exhibit unlimited expansion potential, while previously reported human pancreas organoid (hPO) cultures do not expand efficiently long-term in a chemically defined, serum-free medium. We sought to generate a 3D culture system for long-term expansion of human pancreas ductal cells as hPOs to serve as the basis for studies of human pancreas ductal epithelium, exocrine pancreatic diseases and the development of a genomically stable replacement cell therapy for diabetes mellitus. |
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| Affiliated With | Huch |
| Selected By | Huch |
| Acknowledged Services | |
| Publication Status | Published |
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| DOI | 10.1186/s12861-020-0209-5 |
| PubMed ID | 32098630 |
| WebOfScience Link | WOS:000517440100001 |
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| Display Publisher Download Only | false |
| Visible On MPI-CBG Website | true |
| PDF Downloadable | true |
| Created By | thuem |
| Added Date | 2020-03-09 |
| Last Edited By | thuem |
| Last Edited Date | 2021-12-08 13:27:54.292 |
| Library ID | 7628 |
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| Entry Complete | true |
| eDoc Compliant | true |
| Include in Edoc Report | true |
| In Pure | true |
| Ready for eDoc Export | false |
| Author Affiliations Complete | false |
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