Leveraging Self-supervised Denoising for Image Segmentation.

First Authors Mangal Prakash
Authors Mangal Prakash, Tim-Oliver Buchholz, Manan Lalit, Pavel Tomancak, Florian Jug, Alexander Krull
Corresponding Authors
Last Authors Alexander Krull
Conference Proceedings Volume Title IEEE ISBI 2020 : International Conference on Biomedical Imaging : April 2-7, 2020, Iowa City, Iowa, USA : symposium proceeding
Series Title IEEE International Symposium on Biomedical Imaging
Conference Name IEEE 17th International Symposium on Biomedical Imaging (ISBI)
Conference Location Iowa City, Iowa, USA
Conference Start Date 0020-04-01
Conference End Date 0020-04-05
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Publisher IEEE
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ISBN 978-1-5386-9330-8
First Page 428
Last Page 432
Open Access false
Print Publication Date 2020-05-22
Online Publication Date 2020-05-22
Abstract Deep learning (DL) has arguably emerged as the method of choice for the detection and segmentation of biological structures in microscopy images. However, DL typically needs copious amounts of annotated training data that is for biomedical projects typically not available and excessively expensive to generate. Additionally, tasks become harder in the presence of noise, requiring even more high-quality training data. Hence, we propose to use denoising networks to improve the performance of other DL-based image segmentation methods. More specifically, we present ideas on how state-of-the-art self-supervised CARE networks can improve cell/nuclei segmentation in microscopy data. Using two state-of-the-art baseline methods, U-Net and StarDist, we show that our ideas consistently improve the quality of resulting segmentations, especially when only limited training data for noisy micrographs are available.
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Affiliated With CSBD, Jug, Tomancak
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Acknowledged Services Scientific Computing Facility
Publication Status Published
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DOI 10.1109/ISBI45749.2020.9098559
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Created By thuem
Added Date 2021-02-03
Last Edited By herbst
Last Edited Date 2021-06-21 17:28:13.177
Library ID 7929
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