| First Authors | Corinna Blasse |
|---|---|
| Authors | Corinna Blasse, Stephan Saalfeld, Raphael Etournay, Andreas Sagner, Suzanne Eaton, Eugene W Myers |
| Corresponding Authors | Corinna Blasse, Eugene W Myers |
| Last Authors | Eugene W Myers |
| Journal Name | Bioinformatics (Oxford, England) (Bioinformatics) |
| Volume | 33 |
| Issue | 16 |
| Page Range | 2563-2569 |
| Open Access | false |
| Print Publication Date | 2017-08-15 |
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| Abstract | A significant focus of biological research is to understand the development, organization and function of tissues. A particularly productive area of study is on single layer epithelial tissues in which the adherence junctions of cells form a 2D manifold that is fluorescently labeled. Given the size of the tissue, a microscope must collect a mosaic of overlapping 3D stacks encompassing the stained surface. Downstream interpretation is greatly simplified by preprocessing such a dataset as follows: (i) extracting and mapping the stained manifold in each stack into a single 2D projection plane, (ii) correcting uneven illumination artifacts, (iii) stitching the mosaic planes into a single, large 2D image and (iv) adjusting the contrast. |
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| Affiliated With | CSBD, Eaton, Myers, Postdocs, Predoc first author |
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| Publication Status | Published |
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| DOI | 10.1093/bioinformatics/btx195 |
| PubMed ID | 28383656 |
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| Created By | thuem |
| Added Date | 2017-04-10 |
| Last Edited By | herbst |
| Last Edited Date | 2022-01-31 10:02:25.46 |
| Library ID | 6824 |
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