| First Authors | Olga Vvedenskaya |
|---|---|
| Authors | Olga Vvedenskaya, Yuting Wang, Jacobo Miranda Ackerman, Oskar Knittelfelder, Andrej Shevchenko |
| Corresponding Authors | Andrej Shevchenko |
| Last Authors | Andrej Shevchenko |
| Journal Name | Trends in analytical chemistry (Trends Analyt Chem) |
| Volume | 120 |
| Issue | |
| Article Number | 115277 |
| Open Access | false |
| Print Publication Date | 2018-01-01 |
| Online Publication Date | 2018-10-20 |
| Abstract | Human plasma lipidome has been extensively studied in many pathophysiological contexts with the hope of identifying biomarkers for early diagnostics and monitoring the progression and treatment of a broad spectrum of diseases. However, despite remarkable progress in lipidomics technologies, the concordance of lipidomics measurements between independent laboratories remains limited and not fulfilling the criteria of common laboratory diagnostics. Here we highlighted a few critical aspects of epidemiological studies of the plasma lipidome, including the selection of study cohorts, collection of plasma samples as well as extraction, identification and quantification of lipids. We argue that reporting the abundances of plasma lipids as molar concentrations is a key turning point during the transition of research lipidomics into a common tool of clinical diagnostics. |
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| Affiliated With | Postdoc first author, Postdoc first female, Postdocs, Shevchenko |
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| Publication Status | Published online |
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| DOI | 10.1016/j.trac.2018.10.013 |
| PubMed ID | |
| WebOfScience Link | WOS:000501783700005 |
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| Display Publisher Download Only | false |
| Visible On MPI-CBG Website | true |
| PDF Downloadable | true |
| Created By | shevchenko |
| Added Date | 2018-11-12 |
| Last Edited By | thuem |
| Last Edited Date | 2022-01-11 14:14:06.576 |
| Library ID | 7251 |
| Document ID | |
| Entry Complete | true |
| eDoc Compliant | true |
| Include in Edoc Report | true |
| In Pure | false |
| Ready for eDoc Export | false |
| Author Affiliations Complete | false |
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