| First Authors | Matthias Höllerhage, Linghan Duan |
|---|---|
| Authors | Matthias Höllerhage, Linghan Duan, Oscar Wing Ho Chua, Claudia Moebius, Svenja H Bothe, Kristina Losse, Rebecca Kotzur, Kristina Lau, Franziska Hopfner, Franziska Richter, Christian Wahl-Schott, Marc Bickle, Günter U Höglinger |
| Corresponding Authors | Günter U Höglinger |
| Last Authors | Günter U Höglinger |
| Journal Name | Translational neurodegeneration (Transl Neurodegener) |
| Volume | 14 |
| Issue | 1 |
| Article Number | 27 |
| Open Access | true |
| Print Publication Date | 2025-06-03 |
| Online Publication Date | 2025-06-03 |
| Abstract | Alpha-synuclein (αSyn) is a major player in the pathophysiology of synucleinopathies, which include Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. To date, there is no disease-modifying therapy available for these synucleinopathies. Furthermore, the intracellular mechanisms by which αSyn confers toxicity are not yet fully understood. Therefore, it is of utmost importance to investigate the pathophysiology of αSyn-induced toxicity in order to identify novel molecular targets for the development of disease-modifying therapies. |
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| Affiliated With | Technology Development Studio TDS |
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| Publication Status | Published |
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| DOI | 10.1186/s40035-025-00486-5 |
| PubMed ID | 40457499 |
| WebOfScience Link | WOS:001500673400001 |
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| Created By | thuem |
| Added Date | 2025-06-11 |
| Last Edited By | thuem |
| Last Edited Date | 2025-06-11 11:41:02.67 |
| Library ID | 9010 |
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